Correlation between branched-chain amino acids intake and total lymphocyte count in head and neck cancer patients: a cross-sectional study
Penulis: Yosua Yan Kristian, Rahmat Cahyanur, Yohannessa Wulandari, Wina Sinaga, Widjaja Lukito
Informasi
JurnalBMC nutrition, BMC Nutrition
PenerbitBioMed Central, BMC, BioMed Central Ltd
Volume & EdisiVol. 9,Edisi 1
Halaman86
Tahun Publikasi2023
ISSN20550928
eISSN2055-0928
Jenis SumberGoogle Scholar
Sitasi
Scopus: 9
Google Scholar: 7
PubMed: 9
Abstrak
BackgroundCellular immunity as reflected by total lymphocyte count (TLC) has been proven to be related to overall survival rate cancer patients. Lymphocyte proliferation is regulated, to some extent, by nutritional factor. Branched chain amino acid (BCAA) is documented as one of numerous nutrients that play important role in lymphocyte proliferation through its effect on protein synthesis and DNA replication. Many studies describe the correlation between BCAA and TLC in hepatic cancer patients. This study emphasized the observation of that links in head and neck cancer patients.MethodsEighty-five subjects were included in final analysis, aged 18–75, mostly male, with head and neck cancer who had not received treatment participated in this cross-sectional study at the Dr. Cipto Mangunkusumo General Hospital’s radiation and medical haematology oncology clinic. The BCAAs intake was assessed using a …
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