BackgroundTuberculosis (TB) poses a considerable challenge for people with HIV (PWH), especially in low- and middle-income countries. Even with the availability of effective preventive strategies such as tuberculosis preventive therapy (TPT), the implementation of these measures continues to fall short. Our study explores the perceptions of healthcare workers (HCWs) regarding the barriers and facilitators to TPT implementation in the Philippines and Indonesia.MethodsWe performed 10 focus group discussions and four in-depth interviews with HCWs from June to December 2023. Each discussion and interview lasted between 45 and 120 min. Discussions explored HCWs’ perspectives on the policies, logistics, and prescribing practices related to TPT, as well as their personal experiences, concerns, and suggested improvements. Data were coded using MAXQDA24 qualitative software informed by the tenets of …