Indonesia has a bonus demography challenge. For this reason, youth development should be prioritized by considering the unproductive migration of rural youth groups. Islamic social enterprise (ISE) offers a strategic approach to empowering the youth. This study investigated youth empowerment through vocational training programs provided by two ISE organizations. This is a descriptive qualitative study. Online interviews were carried out from October 2021 to June 2022 involving eight ISE program participants. The research finding shows that ISE supported intellectual, psychological, spiritual, and social skill development. The results also suggest comprehensive support from the government, private sectors, and local communities to ensure the youth groups can be change agents for their villages.