Student Centered e-Learning Environment (SCeLE) is a Learning Management System (LMS) owned and used by the University of Indonesia that functions as an extension or even substitute for a real class environment. This study aims to determine student perceptions of SCeLE as a medium to support teaching and learning activities at the University of Indonesia. The method used in this research is quantitative research methods by distributing questionnaires to 125 respondents. The data processing technique used is a structural equation model that is processed with SmartPLS software against the UTAUT Model. The results of the analysis obtained findings that Performance Expectation, Effort Expectation, and Social Influence have a significant effect on Intention Behavior using SCeLE, while Facilitating Condition has no effect on Intention Behavior; and Intention Behavior has a significant effect on Use Behavior from using SCeLE. The implication of this finding is that the university should make improvements to SCeLE, especially in terms of facility conditions that support its use. This is needed so that the use of SCeLE can be used optimally to support teaching and learning activities for both students and teaching staff. © 2019 IOP Publishing Ltd. All rights reserved.