Background: Acupressure is one of the selfcare methods that is quite simple and noninvasive, which is easy to teach to patients. Due to its ease and minimal side effects, acupressure is often recommended as an appropriate choice for patients to manage various health conditions. However, the integration of acupressure into medical education is still limited, including in Indonesia. The lack of education about acupressure can lead to a lack of understanding among health care providers in teaching acupressure to patients. The objective of this study was to present scientific evidence supporting the efficacy of acupressure in managing various medical conditions and to propose its integration into the medical curriculum. Method: A literature search using the Google Scholar, PubMed, and Embase databases was conducted through Boolean Operators with selected keywords such as acupressure, acupressure training, and health education. Result: A total of six studies obtained met the predetermined inclusion criteria. Through self-administered acupressure counseling and training, there was a significant increase in knowledge scores regarding acupressure and the effects of acupressure on reducing complaints of various ailments. Findings from clinical evidence discussing the use of acupressure have affirmed its effective role in enhancing patient well-being. The integration of education about acupressure as a complementary therapy into the medical education curriculum is becoming increasingly important. Conclusion: Acupressure is effective in addressing various clinical disorders, and through adequate education and training, as well as incorporating acupressure into the medical curriculum, it is expected to provide holistic and effective care to patients. © 2025 Mary Ann Liebert, (NY) LLC.