Hypertension remains a global health challenge. Hypertensive patients frequently suffer high distress and spiritual issues that should be managed, one of interventions is Islamic emotional resilience. The study aimed to examine the impact of the Islamic Emotional Resilience Model on blood pressure and spiritual well-being. This study was a randomized controlled trial (RCT) involving 100 hypertensive patients, with 50 respondents in the intervention group and 50 in the control group. The intervention group received an Islamic Emotional Resilience intervention for three weeks, while the control group continued taking antihypertensive medication. The results demonstrated a significant effect of the i Emotional resilience model on systolic blood pressure (p <0.001), diastolic blood pressure (p <0.001), and spiritual well-being (p <0.001). In the control group, there was a significant difference in systolic blood pressure before and after the study (p <0.001), diastolic blood pressure (p<0.001), but no significant change in spiritual well-being (p=0.939). Islamic Emotional Resilience Model serves as an important complementary approach in managing hypertensive patients. © 2025, Universitas Jenderal Soedirman. All rights reserved.