Pregnant women with anemia and thrombocytopenia are exposed to health risks. Therefore, Levine's conservation theory approach combined with the Health Belief Model theory could be applied to assist pregnant women to optimize their adaptive responses and achieve maximum health. Levine's conservation theory focuses on maintaining an individual's integrity and helping them to adapt to their conditions through the principle of conservation. For the Health Belief Model theory, the involvement and belief of pregnant women are the main aspects required to prevent and treat anemia and thrombocytopenia through their perceived susceptibility, seriousness, benefits, and barriers. Five cases of pregnant women with anemia and thrombocytopenia were provided nursing care that used Levine's conservation and Health Belief Model theory. Doing so resulted in the pregnant women adapting to their conditions and prevented any adverse impacts on their pregnancy. © Asia Pacific Higher Learning Sdn Bhd., Lincoln University College. All Rights Reserved.