Accurate trajectory prediction is essential for ensuring flight safety, autonomous navigation, and efficient control of unmanned aerial vehicles (UAVs). However, existing neural network approaches often focus on a single platform, limiting their generalizability across UAVs with different dynamics. This study evaluates three neural architectures for spatiotemporal trajectory prediction using high-frequency flight data. Two UAV configurations, such as a fixed-wing (Cessna) and a multirotor (Phantom), were simulated in XPlane 11 under identical environmental conditions. Flight data of latitude, longitude, and altitude sampled at 80 Hz were preprocessed using a sliding-window segmentation method to preserve temporal dependencies. Backpropagation Neural Network (BPNN), Recurrent Neural Network (RNN), and Long Short-Term Memory (LSTM) models were trained using standardised preprocessing and tuned hyperparameters. Results show that recurrent models outperform the feedforward BPNN in capturing temporal patterns. For the Cessna dataset, the RNN achieved balanced accuracy with a mean-squared error (MSE) of 5.5 × 10-8, while the LSTM obtained the lowest MSE (2.7 × 10-8). In the more dynamic Phantom dataset, the BPNN remained competitive (MSE ≈ 1.8 × 10-7), whereas RNN and LSTM maintained superior altitude prediction. These results highlight the suitability of lightweight recurrent architectures for real-time UAV trajectory prediction. © 2026 IEEE.