Cleft lip is one of the most common birth defects. Several operations are performed to form a natural lip. A problem with these operations is that the criteria for the facial symmetry are unclear. Based on this background, we propose a method for evaluating the facial symmetry using 4D point cloud data. We evaluate the facial symmetry in two ways. One is based on the temporal changes in the face landmarks. Corresponding points are searched using two local geometric descriptors. The results are approximated to the 3D lines and these slopes are compared to obtain the left-right difference of the movement. The other is based on the center of gravity. The lip part is extracted from the point cloud and divided into subregions. The centroid coordinates are then calculated for each subregion and compared to obtain the left-right difference of the facial structure. The experiment is performed using artificially generated 4D data. As an experimental result, it is shown that our method can find point correspondences with smaller error than comparative methods. © 2023 ICROS.