SNP-array profiling data from breast cancer patients and healthy women's blood DNA samples
Penulis:Â Paramita, Rafika Indah;Â Panigoro, Sonar Soni;Â Fadilah, Fadilah;Â Wanandi, Septelia Inawati;Â Sutandyo, Noorwati
Informasi
JurnalData in Brief
PenerbitElsevier Inc., Data in Brief 59, 111343, 2025
Volume & EdisiVol. 59
Halaman -
Tahun Publikasi2025
ISSN23523409
eISSN2352-3409
Jenis SumberScopus
Sitasi
Scopus: 1
Google Scholar: 1
PubMed: 1
Abstrak
Breast cancer is commonly acknowledged as the primary type of cancer on a global scale, exerting a substantial influence on death rates, particularly in developing countries. The aforementioned discovery provides evidence in favor of the concept that genetic factors may contribute to the onset of breast cancer. This paper presents the unprocessed idat data containing single nucleotide polymorphisms (SNPs) acquired from breast cancer patients and a control group comprising of healthy women. The DNA was obtained from stored blood samples that were collected from a total of 48 female patients diagnosed with breast cancer at Cipto Mangunkusumo National Hospital Jakarta and Dharmais National Cancer Center Hospital Jakarta. Additionally, 24 healthy women were included as control subjects. Subsequently, the DNA samples were subjected to hybridization onto Infinium Asian Screening Array (ASA)’s beadchips. The chip was then subjected to fluorescence intensity measurements using an iScan machine manufactured by Illumina. The data output is produced in the form of a .idat file for each sample. Subsequently, further quality control measures and population stratification analysis were conducted using PLINK (v1.9). After the conclusion of the quality control procedure, 72 individuals and a dataset consisting of 424,285 genetic variants were selected for further analysis. The idat raw data files have been added to the Gene Expression Omnibus (GEO) with accession number: GSE245794 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE245794). © 2025 The Author(s)
Dokumen & Tautan
