The evaluation of speech is important in dentistry, especially in prosthodontics, due to its impact on quality of life. This study aimed to analyze the psychometric properties of the Indonesian Speech Handicap Index (SHI). A cross-sectional study was conducted, and a self-administered questionnaire was disseminated to dental patients in a dental hospital in Indonesia. Internal consistency, test-retest reliability, discriminant validity, and convergent validity were examined to analyze the questionnaire. Furthermore, Mann–Whitney statistical tests were employed to analyze the data. Data were obtained from 32 subjects with an average age of 52.7 ± 16.1 years. The internal consistency of the Indonesian SHI was excellent (Cronbach’s alpha = 0.976). The Indonesian SHI was found to be a reliable and valid clinical tool to measure speech handicap © 2022, Journal of International Dental and Medical Research.All Rights Reserved.