Dyslipidemia management among patients with high and very high cardiovascular risk in Indonesia: a multi-center registry

Penulis: Sunanto Ng, Anwar Santoso, Renan Sukmawan, Erwinanto Erwinanto, Erika Adam
Informasi
JurnalIndonesian Journal of Cardiology
PenerbitIndonesian Journal of Cardiology 46 (2), 2025, Indonesian Heart Association
Volume & EdisiVol. 46,Edisi 2
Tahun Publikasi2025
ISSN28303105
Jenis SumberGoogle Scholar
Abstrak
BackgroundIndonesia, the world's largest archipelago, faces significant challenges in equitable healthcare delivery due to its geographical and infrastructural disparities. Atherosclerotic Cardiovascular Disease (ASCVD) remains the leading cause of mortality, with over 659,000 deaths recorded in 2019. Effective dyslipidemia management is crucial for preventing adverse ASCVD events. Unfortunately, the lack of implementation of an updated national lipid management registry might hinder optimal strategy for the adverse events. This study evaluated dyslipidemia cholesterol management practices among high-and very high-risk patients across the country.MethodsThe study recruited 322 patients from eight centers across six provinces in Indonesia between May 2022 and March 2023. Patients were stratified based on the ASCVD risk and followed over three visits. Baseline clinical characteristics, lipid profiles, and treatment regimens were analyzed. Descriptive statistics summarized continuous and categorical variables, and low-density lipoprotein cholesterol (LDL-C) achievement was assessed.ResultsOf the 322 patients, 98.8% were very high-risk, with only 4.9% achieving< 55 mg/dL and 21.2% achieving< 70 mg/dL. Moderate-intensity statins were the most prescribed (51.2%), followed by high-intensity (36.6%). LDL-C reduction was most pronounced in private insurance patients, achieving a mean LDL-C of 69.8 mg/dL at the third visit compared to 98.9 mg/dL in National Health Insurance (Jaminan Kesehatan Nasional/JKN) participants. Missed visit rates increased over time, with 57.5% of patients missing the third visit, predominantly among …
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