Reconstruction in post-mandibular resection patients using plate reconstruction is commonly performed in several hospitals in Indonesia. Some complications that can occur after reconstruction of the mandible can be expose plates, plate fractures and infection. The purpose of this study will look for several factors that influence the occurrence of these complications. A retrospective study from 2012–2017 taken from medical records. Data from 69 patients with available information on the prevalence of complications 21.73% (15/69) with an average observation time 15.4 months. There was an effect of smoking history 7.2% (p = 0.00) and age factor 21% (p = 0.00) on the occurrence of postoperative complications with hazard ratio of smoking history 9.19 and age factor 10–20 years compared to over 60 years is 153.8. The plate survival rate in patients who do not smoke is above 80% in the first 2 years, the third year is 60% and after that it can decrease by 20–40%. Smoking and age factors influence the incidence of post-reconstruction mandibular complications. If possible, mandible reconstruction using a reconstruction plate is temporary procedure, it is necessary to consider the use of either vascularized or non-vascularized grafts. © 2021. All rights reserved.