The solar power plant is an alternative to the provision of environmentally friendly renewable electricity, especially in the tropics, which are sufficiently exposed to the sun throughout the year. However, environmental conditions such as rainfall, solar radiation, or clouds may affect the output power of photovoltaic (PV) systems. These factors make it difficult to know whether PV can meet the needs of the existing load. This research develops a model to predict the output power of a 160 x 285W PV system located in the tropics and has certain environmental conditions. The prediction development is supported by the Python programming language with a single hidden layer and two hidden layers Neural Network, as well as the traditional Multiple Linear Regression tools. The simulation results show that the two hidden layers Neural Network method has a higher level of accuracy compared to the single hidden layer and Multiple Linear Regression as seen from the value of R2, MSE, and MAE. © Published under licence by IOP Publishing Ltd.