Objective: The objective of this study was to assess the quality of life (QoL) in spinal cord injury (SCI) with neurogenic bladder problem in Indonesia. Method: This descriptive study, involving 55 participants, used the WHO Quality of Life brief form (WHOQOL-BREF) to measure QOL in each of four domains: physical, psychological, social relationships, and environment. Results: The mean scores of QOL after analysis of the data were 11.41 for the physical domain, 12.38 for the psychological domain, 12.22 for social relationships, and 11.55 for environment. The total mean QOL score was 47.55, which is a relatively low score compared to generally healthy adults. Conclusion: Among the four domains of QOL, the physical domain had the lowest mean score. These results highlight the necessity of exploring the factors related to QOL for SCI patients with neurogenic bladder problem. © 2019 Elsevier España, S.L.U.