In order to achieve a cleaner environment, CO2 from power plants’ flue gas can be processed through the carbon capture, utilization, and storage (CCUS) process. This study simulates the CO2 conversion to produce dimethyl ether (DME) using an indirect method using Aspen HYSYS V.11. The simulation modeled the CO2 capture process using the acid gas-chemical solvent fluid package, while other processes were modeled with the Peng-Robinson fluid package. A monoethanolamine (MEA)-to-flue gas ratio of 4:1 achieves a 99.99 % CO2 captured and low MEA discharge to the environment of 0.01 tons/h (0.15 kg/ton CO2 captured). In the meantime, methanol synthesis at 270 °C 70 bar in a plug flow reactor yields 19.36 % methanol and a distillation column with 20 stages and a reflux ratio of 2 rectifies it to 99.5 %-mol methanol (specific energy consumption of 4.22 MWh/ton). In the DME synthesis, an 80.70 % methanol conversion at 260 °C 15 bar requires 10 stages and a reflux ratio of 4 in the distillation column to yield 99.8 %-mol DME (specific energy consumption of 0.945 MWh/ton). Overall, this simulation highlights energy-efficient methods for sustainable DME production as well as significantly reducing CO2 emissions. The findings reveal that converting CO2 from power plants’ flue gas to DME can effectively reduce greenhouse gas (GHG) emissions. © 2025